Cyclooxygenase (COX)-2 selective inhibitors + ACE inhibitors: a new protocol in the treatment of heavy proteinuria.
Riferimento bibliografico:
(Abstarct book from the Congress of Nephrology June 8-12, 2003 Berlin, Germany) Nephrology Dialysis Transplantation Volume 18, Supplement 4 M253 June 2003
(Abstarct book from the Congress of Nephrology June 8-12, 2003 Berlin, Germany) Nephrology Dialysis Transplantation Volume 18, Supplement 4 M253 June 2003
Data pubblicazione:
Autori: Costanzi S, Sturniolo A, Fulignati P, Passalacqua S, Staffolani E, D’Alonzo S, Splendiani G.
Non steroidal anti-inflammatory drugs (NSAIDs) are surely useful in the treatment of proteinuria, but these agents may cause deleterious effects om kidney function as maintenance of renal perfusion and glomerular filtration; moreover often they induce gastrointestinal toxicity. Recent studies have demonstrated that COX-2 is constutively expressed in renal tissues;
Cyclooxygenase (COX)-2 selective inhibitors...pdf 