The Italian Registry for Therapeutic Apheresis. A report from the Apheresis Study Group of the Italian Society of Nephrology.

Riferimento bibliografico:
J Clin Apher. 2005 Jul;20(2):101-6.

Data pubblicazione: 07/2005

Autori: Passalacqua S, Staffolani E, Busnach G, Roccatello D, Pasquali S, Cappelli P, Liuzzo G; Apheresis Study Group of the Italian Society of Nephrology.

Many clinical indications and different technical issues have been reported on therapeutic apheresis: much criticism has also been recorded in several instances, mainly due to the lack of large clinical trials to validate collected data. A Registry where all the available data can be organized and analyzed therefore becomes a priority for all the professionals involved in apheresis. The purpose of this report is to describe the data submitted from 1994 to 2004 from 15,285 treatments on 1,477 patients from 44 Centers, including mainly, but not exclusively, Nephrological Units, collected by the Apheresis Study Group of the Italian Society of Nephrology in 15 Italian regions. Plasma exchange accounted for 56.2% of the procedures, and of these 50.4% were performed by filtration. Plasma treatment was used in 40.1% of procedures, namely with Protein A immunoadsorption (14.6%), LDL-Cholesterol dextran sulfate adsorption (9.7%), and semiselective cascade or double filtration (12.6%). Cell apheresis, limited to photopheresis, was used in 0.85% of cases, and whole blood treatment (direct adsorption lipoprotein, and molecular adsorption recirculating system) in 2.7%. The procedures analyzed here account for less than 20% of estimated therapeutic apheresis performed in Italy, according to the national survey of activity performed for year 2000 by the Italian Apheresis Society. Notwithstanding that the data are largely incomplete, they are sufficiently informative for a definite trend: plasma treatment with filtration on fractionation filters and adsorption must be used as often as possible, instead of plasma exchange, thus obtaining the most selective removals.

Collaboratori
Giusti Bruna Pia Osp. S.D. Donato Nefrol. e Dialisi Arezzo Mauro Ragaiolo Osp. C.G. Mazzoni Nefrol. e Dialisi Ascoli Piceno Tommaso De Palo Osp. Giovanni XXIII Nefrol. e Dialisi Pediatrica Bari Carlo Manno Consorziale-Policlinico Nefrol. e Dialisi Pediatrica Bari Alfonso Ramunni Policlinico Di Bari Nefrol. e Dialisi Bari Riccardo Losappio Osp. Umberto I Nefrol. e Dialisi Barletta Sonia Pasquali Policlinico S. Orsola Malpighi Nefrol. e Dialisi Bologna Felice Fortina Osp. SS. Trinita Nefrol. e Dialisi Borgomanero Antonio Barracca Osp. Brotzu Nefrol. e Dialisi Cagliari Salvatore Alba Osp. Cardarelli Nefrol. e Dialisi Campobasso Gabriele Liuzzo Osp. Tomaselli Nefrol. e Dialisi Catania Lorenzo Di Liberato Osp. SS. Annunziata Nefrol. e Dialisi Chieti Augusto Di Silva Osp. Di Formia Nefrol. e Dialisi Formia Franco Scaccia Osp. Umberto I Nefrol. e Dialisi Frosinone Giancarlo Marinangeli Osp. Civile Nefrol. e Dialisi Giulianova Riccardo Giusti Osp. Campo Di Marte Nefrol. e Dialisi Lucca Pierpaolo Toffoletto Osp. Umberto I Nefrol. e Dialisi Mestre Carlo Antozzi 1st Naz. Neurol C. Besta Neurolgia Milano Ghil Busnach Osp. Niguarda Ca’ Granda Nefrol e Dialisi Milano Giuseppe Pastore Osp. S. Giacomo Nefrol e Dialisi Monopoli Carlo De Pascale Osp. D. Cotugno Nefrol. e Dialisi Napoli Dario Zazzaro Osp. G.B. Grassi Nefrol. e Dialisi Ostia Luciangela Calvisi Osp. A. Segni Nefrol e Dialisi Ozieri Poisetti Pier Giorgio Osp. Civile Nefrol. e Dialisi Piacenza Rodolfo Puccini Osp. S. Chiara Nefrol Dialisi Trapianto Pisa Maurizio Ciccarelli Osp. Reggio Calabria Nefrol. e Dialisi Reggio Calabria Michele Ferrannini Policlinico Tor Vergata Nefrol. e Dialisi Roma Carlo Meloni Osp. S. Eugenio Nefrol. E Dialisi Roma Gilnardo Novelli Universita` La Sapienza II Patologia Chirurgica Roma Stefano Passalacqua C.I. Columbus U.C.S.C. Nefrol. e Dialisi Roma Renzo Pretagostini Policlinico Umberto I Nefrol. Dialisi Trapianto Roma Elios Russo Gaspare Policlinico Umberto I Nefrol E Dialisi Roma Cladio Stefanutti Universita` La Sapienza Ambulatorio Aferesi Roma Luigi Moriconi Osp. Valdarno Inferiore Nefrol. e Dialisi S. Miniato Maria Cossu Osp. SS Annunziata Nefrol. e Dialisi Sassari Giulio Monaci Policlinico Le Scotte Nefrol Trapianto Siena Alberto Scatizzi Osp. SS. Annunziata Nefrol. e Dialisi Taranto Roberto Laudati Osp. Oirm S. Anna Centro Trasfusionale Torino Massimo Milan Osp. G. Bosco Immunoematologia Torino Dario Roccatello Osp. G. Bosco Cento Cmid Leinaudi Torino Antonio Niccolini Osp. S. Chiara Nefrol. e Dialisi Trento Cristina Maresca Maria Osp. S. Maria Dei Battuti Nefrol. e Dialisi Treviso Mietta Meroni Osp. Di Vimercate Nefrol. e Dialisi Vimercate Sandro Feriozzi Osp. Grande Degli Infermi Nefrol. e Dialisi Viterbo